About Atlas Genetics’
io® system

Our pioneering, flexible diagnostic instrument and disposable cartridge system is designed for decentralised laboratory, point-of–care and other near-patient settings. It provides a fast, easy-to-use and accurate affordable solution to screening for the presence of STIs, where rapid diagnosis is essential for effective treatment and control.

Find out more

Rapid electrochemical identification of pathogenic Candida species. Journal of Medical Microbiology. September 2009 (Muir, A. et al., 2009.)

This study describes the development of a novel assay to detect fungal DNA and identify the most clinically relevant invasive human pathogenic fungi to the species level using oligonucleotide probes, labelled with electrochemically active groups, and solid-state electrodes. A panfungal probe designed against the 18S rRNA gene region, capable of detecting all fungal pathogens tested, and species-specific probes, designed against the ITS2 region for detection of the five Candida species most commonly encountered in the clinical setting (Candida albicans, Candida glabrata, Candida parapsilosis species complex, Candida krusei and Candida tropicalis), are described. When tested with PCR-amplified DNA from both type and clinical strains of the relevant species, the probes were able to positively identify the relevant fungi, indicated by production of a current significantly elevated above the background reading. No cross-reactivity was observed with any of the species-specific probes when compared with nine non-target Candida species or in the presence of human DNA equivalent to an equal number of ITS2 targets. The panfungal probe gave results that were similarly positive against 15 other fungal species and also did not cross-react with human DNA. The limit of detection of the assay was shown to be approximately 1 genome equivalent for all probes using extracted genomic DNA.

Access the full PDF publication, sign into "the Hub" now - click here

Get access to all the latest industry insight   SIGN-UP TO THE ATLAS GENETICS RESOURCE HUB

Contact us

Atlas Genetics
Derby Court 
Epsom Square 
White Horse Business Park 
Trowbridge, Wiltshire 
BA14 0XG 
United Kingdom 

 

+44 (0)1225 717930 
info@atlasgenetics.com

FIND US


logos

Follow us



Hear more about the ways that 
the Atlas Genetics io® can
assist you 

REQUEST MORE PRODUCT INFORMATION